Abstract: Given the severe impacts of supply suspension and supply cutoff of foreign CNC systems on China’s machine tool industry, this paper puts forward a domestic substitution technical solution, which utilizes the PMC axis function of the HNC-848Di CNC system to control the chain-type tool magazine of five-axis horizontal machining centers. Rapid positioning of the tool magazine and linked tool change control are realized through parameter configuration, PMC axis mode switching, G/F register access, and programming with the AXISMVTO and AXISMOVE functional instructions.In addition, structural optimization design is implemented for the tool magazine. After renovation, the tool change cycle time is shortened from 100 s to 50 s, and the production cost of the tool magazine is reduced by 37.5%. This study can serve as a reference for replacing imported CNC systems with domestic counterparts.