Abstract: In this paper, a special storage box for large underwater vehicles with special requirements for storage environment is designed. Firstly, the optimal structure scheme of the storage box is determined by analyzing and comparing the advantages and disadvantages of the existing technology and various structures, and the overall design is carried out to determine the implementation scheme. According to the design process, the tightness, structural strength and monitoring device of the storage box are designed, and the experimental verification is carried out. The test data are analyzed and summarized, which provides an application reference for the long-term storage of large underwater vehicles.